Why do patterns emerge in nature, and what do they reveal about underlying processes? From the stripes on a zebra to waves in the ocean, patterns offer insight into complex systems. In our study, we explore how single-celled amoebae generate dynamic patterns of a protein called Rac1, which controls cell movement. Through mathematical modeling and experiments, we analyze how Rac1 switches on and off along the cell membrane to create waves and oscillations. These patterns not only help us understand how cells navigate their environment but also reveal the internal reaction networks that drive cellular behavior.
This talk will introduce the basics of cell motility, our modeling methods, and the role of randomness, or “noise,” in pattern formation. We’ll also look ahead to future work involving a systematic search through model space using equation discovery methods.
Zoom link: https://us04web.zoom.us/j/79055582790?pwd=zuc3RsogHj0Gex43ilMEx8TOiETGxp.1